Antioxidants against cancer by Ralph W. Moss

By Ralph W. Moss

Learn the way antioxidants decrease the side-effects of chemotherapy and will even make it greater.

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P~ysician-in-chief at. Memorial' Sloan-Kettering. Cancer Center in New Xork. Dr. dy was ":t:ecbnicalJy :ftawed. ••The data is all over the pJace~ ••It doesn't make any sense•••" Dr. Mark Levine, chief of molecular· and clinical nutrition at the National Institutes of Health, told reporters, "How Gm I put this simply? mls 44 VITAMIN C flawed because researchers measured the level of vitamin C in the blood but not the level of vitamin C in the cells. Dr. Jeffrey Blumberg, chief of the antioxidant research lab in the Human Research Center at Tufts University in Boston, said that 500 milligrams is a reasonable amount to take.

Signs of mutated p5 3 genes are found in about half of all cancers and p5 3 mutations are generally a sign of aggressive tumors. The same scientists also looked at the influence of vitamins on the p53 status of smokers. " But among those who had smoked more than 29 years, vitamin use did not significantly reduce such mutations. (50) The implications of this are profound. We think of genetic mutations as predetermined or unchangeable. Yet in this study, the genetic expression of cells was altered for the better by the addition of a few antioxidants.

In the late 1970s, Dr. Prasad noticed that sodium ascorbate (a form of vitamin C) had varying effects on different chemotherapy drugs. Using neuroblastoma cells, he found that vitamin C added to the cancer-killing 48 VITAMIN C effects of many well known anticancer agents such as dacarbazine, 5-FU, bleomycin, tamoxifen, as well as X rays. A mixture of vitamin C, betacarotene and vitamin E showed even more benefit. (359, 360) It is ironic that one of the few negative tests on the interaction of vitamin C and chemotherapy came from Dr.

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